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10.2337/diabetes.54.1.146 11 BragazziN

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Large human trials (such as the SUSTAIN and STEP programs) have not shown meaningful increases in fracture risk or significant reductions in bone mineral density directly attributable to semaglutide use

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After treating 3T3-L1 cells with GLP-1, some scholars found that the number of small and medium-sized adipocytes increased

Intestinal glucose infusion increases portal levels of GLP-1, and coinfusion of exendin-9, a GLP-1R antagonist, abolishes the ability of both intestinal fatty acids and glucose infusion to lower hepatic glucose production 130,131